Timeline
The ideas behind AI_PREMie came into being in 2015 when University College Dublin colleagues, Professor Patricia Maguire and Professor Fionnuala Ní Áinle, met for a coffee.
An Irish Times article from 2021 documented this meeting:
...Ní Áinle talked about her experiences as a consultant haematologist at the Rotunda, seeing women with severe pre-eclampsia. They discussed the potential for biomarkers in the blood to serve as an early warning system and went on to confirm this with a study showing significant differences in the platelets of pregnant women suspected of having pre-eclampsia and healthy women of the same age. Armed with this evidence and a large amount of related data, the team was able to take its research to the next level when it applied for Science Foundation Ireland’s AI for Societal Good Challenge funding. Using an interdisciplinary approach, it could unlock new insights with data analytics and machine learning techniques.
Irish Times
Explore the timeline of developments since the AI_PREMie project’s inception.
Patricia Maguire, Ana Le Chevillier, Cora McCann and Brian Mac Namee represented the AI_PREMie team at SAS Innovate in London. Patricia Maguire and Ana Le Chevillier were invited to speak about AI_PREMie at the event.
Ana Le Chevillier took part in a panel discussion speaking on the deployment of AI in healthcare, using AI_PREMie as an example.
Ana Le Chevillier represented AI_PREMie at SLAS Europe 2024, speaking on AI and Computational approaches in healthcare.
Professor Patricia Maguire discussed the importance of AI in drug discovery.
Ana Le Chevillier discussed AI’s role in Disease Prediction, highlighting AI_PREMie, at the National Healthcare Outcomes Conference 2024.
Professor Patricia Maguire was delighted to represent University College Dublin at the Irish Medical Organisation annual conference, speaking on AI in healthcare and AI_PREMie.
Professor Patricia Maguire collaborated with SAS to create a video for Microsoft, featuring AI_PREMie in the Microsoft AI Showcase for Healthcare.
SAS showcased AI_PREMie’s groundbreaking research to transform pre-eclampsia diagnosis with SAS Viya on Microsoft Azure.
UCD's Associate Professor Brian MacNamee and Professor Maguire, in collaboration with Northeastern University, are among the first initiatives funded through the new institutional collaborative relationship between the two universities.
Professor Gerardine Doyle and Dr Kate Cullen discussed our pioneering research on the cost analysis of preeclampsia care at the prestigious 2024 Public Conference in Venice.
Professor Patricia Maguire was delighted to speak about AI_PREMie at the 20th National Health Summit 24.
Professor Patricia Maguire and Associate Professor Brian Mac Namee were invited to speak about AI_PREMie to the Northeastern University PROTECT study group in Puerto Rico.
Professor Patricia Maguire spoke about AI_PREMie at the launch of Translational Medicine Alliance Ireland (TMAI) at St James’s Hospital, Dublin.
Professor Patricia Maguire and AI_PREMie were showcased on the RTE documentary "Game Changer: AI and You.”
AI_PREMie was included in the Business Post article, “The Irish AI Companies You Need to Know.”
AI_PREMie was honoured to be included in the Science Foundation Ireland Little Book of Irish Research launched by Minister Simon Harris during Science Week 2023
Ana Le Chevillier was thrilled to be a finalist in the Young AI Role Model category for the 2023 AI Awards.
Ana Le Chevillier was featured on the AI Ireland podcast series, where she discussed her role in AI_PREMie and the impactful contributions of AI in healthcare.
Dr. Luisa Weiss was an invited speaker at SLAS, where she presented on AI_PREMie in her talk titled "Platelet Releasate Proteomics – A Robust Biomarker Discovery Platform" within the "Identification of Biomarkers using Omics" session held in Basel, Switzerland.
AI_PREMie was included in the Autumn/Winter edition of UCD Today.
Professor Patricia Maguire was honoured to be a keynote speaker at the HEAnet’23 Conference entitled ‘Connectivity Matters’, Killarney.
Professor Patricia Maguire was an invited panellist at the IPHA event in association with EY entitled ‘Practical Applications of AI in Healthcare.
Professor Patricia Maguire presented her work on AI_PREMie to a large group of Data and Analytics Professionals as part of the NHS England TechTalk discussion series.
Professor Patricia Maguire participated in the Irish Pharmaceutical Healthcare Association video campaign “Innovate for Life” in association with Amgen Pharmaceuticals.
AI_PREMie was very honoured to win the AI Innovation of the Year Award at The Public Sector Digital Transformation Awards 2023.
Professor Patricia Maguire was a visiting Professor at Northeastern University, Boston, and gave a seminar at the Roux Institute at Northeastern University, Maine, entitled ‘The 100 Platelet Releasates Project (100 PREPs).
In an article titled 'A new chapter' by UCD Connections, President Orla Feely discussed AI_PREMie as one of the pioneering AI uses in the university.
Professor Patricia Maguire discussed AI_PREMie in an interview with John Patrick Shaw (Ireland Head, Carelon Global Solutions).
AI_PREMie was thrilled to be awarded the Best Social Impact Award.
Professor Patricia Maguire was honoured to be awarded the Irish Women’s Award for Services in Medicine 2023.
Ana Le Chevillier discussed AI_PREMie at the Women in Data Science event held in Dublin.
AI_PREMie was featured in an RTE Prime Time programme on the impact of Artificial Intelligence.
Precision medicine has the potential to benefit even more patients.
Some of the AI_PREMie team presented at the ISEV 2023 (International Society for Extracellular Vesicles) in Seattle.
AI_PREMie has been rated excellent in the UNESCO Global Top 100 AI projects addressing the 17 UN sustainable goals. AI_PREMie is honoured to be awarded one of the top 30 projects in the IRCAI's international list of AI solutions for reaching the 17 SDGs.
AI_PREMie - a smart approach to predicting preeclampsia.
‘Our test will save lives’, says Director of UCD’s Institute for Discovery.
AI_PREMie was featured as a case success story at the Open Clouds for Research Environments (OCRE) GÉANT Cloud Forum.
Combining Irish-US Strengths in health tech research for better outcomes.
Professor Patricia Maguire was honoured to present her research work at the Gordon Conference
Professor Patricia Maguire was honoured to be nominated for AI Project Leader of the Year at the CIO Awards
Contributor to AI in Clinical Medicine: A Practical Guide for Healthcare Professionals
AI_PREMie won best research in obstetrics and gynaecology at UCD SurgSoc annual conference.
Brian MacNamee presented ‘a game changer in tackling preeclampsia’ at Insight Winter Lecture on the ‘superpower’ of #machinelearning event
AI_PREMie featured in the SASsoftware and Microsoft joint whitepaper highlighting co-developed clinical decision support tools enabled by advanced analytics and AI in the cloud.
Professor Patricia Maguire discusses the AI_PREMie PET diagnosis tool with Pat Kenny.
Listen on Spotify.
AI_PREMie won awards in both categories that it was nominated for:
1). Best Application of AI to Achieve Social Good
2). Best Application of AI in an Academic Research Body.
Challenge funding is playing a key role in honing research projects across Ireland, according to researchers, including AI_PREMie.
The AI_PREMie team attended the ISTH2022 (the 30th Congress of the International Society on Thrombosis and Haemostasis) in London, UK.
AI_PREMie was honoured to be nominated for the Social Impact Award at the Analytics and AI Awards 22.
Professor Patrica Maguire discusses the AI_PREMie PET diagnosis tool.
AI_PREMie launched a campaign for World Preeclampsia Day to highlight this life-threatening disease and also promote the work done by the AI_PREMie team to develop a diagnostic tool for preeclampsia.
Research Impact Case Study Competition - runner up.
The Irish Universities Association has partnered with RTÉ and New Decade TV to bring Ireland’s Change Makers, the most transformative research-led projects and the inspiring people behind them, to Irish television this coming January and February 2022.
The series will showcase the remarkable and lasting public impact of leading research projects by eight universities in Ireland in areas such as children’s health, health technology, education, youth justice, gender equality and inclusion, as well as the environment.
Patricia Maguire spoke to Newstalk Radio's Late Breakfast presenter Shane Beatty about her preeclampsia research, ahead of the RTE TV show Change Makers which features her AI_PREMie project.
On this episode, Greg speaks with Professor Patricia Maguire, Biomedical Scientist and Director of University College Dublin’s Institute for Discovery. Maguire’s research focuses on platelets, an interest that began 25 years ago when her father suffered his first heart attack and she recognized the need for better diagnostics in the clinic.
Researchers Are Discovering How to Predict – and Maybe Treat — Pregnancy Complications Early On.
Improving Maternal Health through AI and Biomedical Science | Health Pulse Podcast
"Using platelets as little health sensors in our blood" - The Irish Times.
"Using platelets as little health sensors in our blood" - Recruitment for Technology
Winner of the NovaUCD Innovation of the Year Award 2021.
UCD team using AI to help diagnose pre-eclampsia and save lives.
AI_PREMie: A Novel Risk Stratification Tool for Preeclamptic-toxaemia
SFI AI for Societal Good Challenge
Supports interdisciplinary teams to develop novel, potentially disruptive AI-based solutions that address significant national and global societal challenges.
Read more on SFI.
Upon activation platelets release a host of soluble and vesicular signals, collectively termed the ‘platelet releasate’ (PR). The contents of this PR play a significant role in haemostasis, wound healing, tissue regeneration, inflammation, and pathologic sequelae.
Read the full article on Science Direct.
Read the full article in Proteomics Clinical Applications.
Upon activation, platelets release a powerful cocktail of soluble and vesicular signals, collectively termed the "platelet releasate" (PR). Although several studies have used qualitative/quantitative proteomic approaches to characterize PR; with debated content and significant inter-individual variability reported, confident, and reliable insights have been hindered. Using label-free quantitative (LFQ)-proteomics analysis, a reproducible, quantifiable investigation of the 1U mL−1 thrombin-induced PR from 32 healthy adults was conducted.
Read the full article in Proteomics.
Retrospective secondary analysis of an observational study in an Irish tertiary referral centre with 9000 deliveries annually. The MPV of 27 women with EOPE was compared to 19 unaffected controls. The inclusion criteria for the disease state was the development of EOPE defined by the National Institute for Health and Care Excellence (NICE) guideline, as new onset hypertension presenting after 20 weeks and prior to 34 weeks with significant proteinuria.
Read the full article in the Journal of Perinatal Medicine.
Early onset preeclampsia (EOP) is a pregnancy-specific proinflammatory disorder that is characterised by competing thrombotic and bleeding risks. It was the aim of this study to characterise thrombin generation, a major determinant of thrombotic and bleeding risk, in order to better understand the haemostatic balance in patients with EOP.
Read the full article on PubMed.
